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  • Chronic hepatitis is a progressive inflammatory liver condition. Although there are many potential causes, often the underlying cause is not identified. Initially there may be no clinical signs but as liver scarring increases, signs can include decreased appetite, vomiting, diarrhea, abnormal bleeding and a bloated appearance. Diagnosis, treatment and prognosis are discussed.

  • Chronic kidney disease (CKD) is the inability of the kidneys to efficiently filter the blood of waste products. In dogs, chronic kidney disease is associated with aging. For most small dogs, the early signs of kidney disease occur around 10 to 14 years of age, while it may occur in large dogs as early as seven years of age. This handout describes clinical signs, causes, diagnosis, treatment, and nutritional management.

  • Chronic lymphocytic leukemia is a slowly progressing cancer of a type of white blood cell called a lymphocyte. It can develop at any age but is more typically detected in middle-aged to senior dogs. It also seems to be more prevalent in German Shepherds and Golden Retrievers. This disease is often asymptomatic and detected on routine lab screening. Further diagnostic procedures, as well as treatments and prognoses, are described in this handout.

  • Cimetidine is given by mouth and is used off label in cats, dogs, small mammals and horses to treat various gastrointestinal conditions related to acid production, such as ulcers and reflux. Side effects are uncommon and have not been documented in animals. Do not use in pets that are allergic to it or other histamine2 blockers.

  • Ciprofloxacin ophthalmic (brand name Ciloxan(R)) is an antibacterial agent used in the treatment of eye infections in dogs and cats. Its use in dogs and cats is off label or extra label. This medication should not be used in dogs that are allergic to quinolones. Some medications may interact with ciprofloxacin, so it is important to tell your veterinarian about any medications that your pet is taking. If a negative reaction occurs, please call your veterinary office.

  • Ciprofloxacin is a systemic fluoroquinolone antibiotic used to treat bacterial infections. It is often given by mouth, but an injectable form is also available. The most common side effect is gastrointestinal distress, but other side effects are possible. It is contraindicated in young or dehydrated pets, or in pets with liver or kidney disease. It should not be the first-choice fluoroquinolone for veterinary patients.

  • Cisapride is used off label and is given by mouth to treat gastrointestinal motility disorders in cats, dogs, and small mammals. Common side effects include vomiting, diarrhea, and abdominal discomfort. Do not use in pets that are allergic to it or in pets with conditions that would be made worse by increased intestinal movement. If a negative reaction occurs, please call your veterinary office.

  • Cisplatin is a chemotherapy drug used to treat various forms of cancer and solid tumors in animals. It is prescribed off-label for use in dogs, horses, birds, and reptiles. It should not be used in cats due to potentially fatal side effects. Cisplatin is administered by injection, typically IV into the vein, by trained veterinary staff.

  • Clarithromycin is given by mouth and used off label to treat certain bacterial infections in several animal species. Do not use in pets that are allergic to it or other macrolide antibiotics, in rabbits, gerbils, guinea pigs, hamsters, or horses more than four months old.

  • Clemastine is a first-generation antihistamine used in the relief of allergy symptoms in cats and dogs. It is used off label in veterinary medicine. Clemastine comes tablet and liquid forms to be given orally.